EXERCISE HEAT-STRESS IN RATS - PERFORMANCE AND BIOCHEMICAL EFFECTS

被引：5

作者：

BOURDON, L

DALEO, P

PERRAULT, H

POUZERATTE, N

CURE, M

机构：

[1] Unité de Bioénergétique et Environnement, Centre de recherches du Service de santé des armées, La Tronche, 38702

来源：

JOURNAL OF WILDERNESS MEDICINE | 1994年 / 5卷 / 02期

关键词：

EXERCISE; HEAT-EXHAUSTION; DISTURBED MENTAL STATUS;

D O I：

10.1580/0953-9859-5.2.153

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Disturbed mental status (DMS) is the most obvious sign of exertional heatstroke in humans, and is one of the main complications of severe exercise heat-stress (SHS). The cause of exertional heat-stroke has been attributed to many factors such as thermoregulatory failure or impairment of muscular function. This investigation was designed to assess muscle energy metabolism in two groups of rats running at 34-degrees-C. One group (n = 17) stopped because of DMS (SHS rats), while the other group (n = 21) stopped because of mild or moderate exercise heat-stress (MHS rats). SHS rats ran longer and had a higher final rectal temperature (T(re)): 66.5 +/- 4.2-degrees-C vs 47.3 +/- 3.8-degrees-C, p < 0.05 and 42.7 +/- 0.12-degrees-C vs 42.2 +/- 0.15-degrees-C, p < 0.05, respectively. SHS rats also had a slower rate of change of T(re) (0.054 +/- 0.007-degrees-C min-1 vs 0.072 +/- 0.008-degrees-C min-1) and a lower mean rate of dehydration: 0.065 +/- 0.006 vs 0.084 +/- 0.005 % bodyweight min-1, p < 0.05. There were no significant differences between the two groups for skeletal muscle concentration of high energy phosphates and glycogen, but lactate was higher in SHS than in MHS rats: 25.0 +/- 6.7 vs 11.8 +/- 1.6 mumoles per mg protein respectively, p < 0.05. These data suggest that DMS may be linked to T(re) and that there is muscular functional impairment caused by SHS.

引用

页码：153 / 162

页数：10

共 25 条

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