SERUM ALBUMIN PRODUCTION BY HEPATOMA CELLS IN CULTURE - DIRECT EVIDENCE FOR STIMULATION BY HYDROCORTISONE

被引：29

作者：

BANCROFT, FC

LEVINE, L

TASHJIAN, AH

机构：

[1] Pharmacology Department, Harvard School of Dental Medicine, Department of Pharmacology, Boston

[2] Graduate Department of Biochemistry, Brandeis University, Waltham

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1969年 / 37卷 / 06期

关键词：

D O I：

10.1016/0006-291X(69)90235-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Addition of hydrocortisone to the medium of a clonal strain of rat hepatoma cells (MH1C1) stimulated their production of serum albumin. The stimulated rate of production reached a maximum by 50 hours, at which time it was about four times the rate in control cultures. Stimulation was observed at a hydrocortisone concentration as low as 10-7M. Removal of hydrocortisone from the medium caused a return of the rate of albumin production to that in control cultures. © 1969.

引用

页码：1028 / &

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