FIBER-LASER IR LUMINESCENCE DIAGNOSTICS OF MALIGNANT-TUMORS USING RARE-EARTH PORPHYRINS

被引：73

作者：

GAIDUK, MI

GRIGORYANTS, VV

MIRONOV, AF

RUMYANTSEVA, VD

CHISSOV, VI

SUKHIN, GM

机构：

[1] MV LOMONOSOV FINE CHEM TECHNOL INST,MOSCOW 119831,USSR

[2] PA GERTSEN ONCOL RES INST,MOSCOW 125284,USSR

来源：

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY | 1990年 / 7卷 / 01期

关键词：

laser-fibre method; Luminescence contrast; malignant tumours; ytterbium porphyrins;

D O I：

10.1016/1011-1344(90)85139-N

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

To eliminate the masking effect of the background luminescence of endogenic substances in biological tissues and to increase the luminescence contrast values of malignant tumours, sarcoma-implanted mice were administered with ytterbium porphyrins instead of free porphyrin radicals. This was followed by in vivo luminescence localization of tumours using fibre-laser spectrofluorometry. The luminescence contrast values obtained reached 10-45 which is evidently not a limit. © 1990.

引用

页码：15 / 20

页数：6

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