OXIDATION-STATE OF TECHNETIUM IN BONE SCANNING AGENTS AS DETERMINED AT CARRIER CONCENTRATION BY AMPEROMETRIC-TITRATION

被引：16

作者：

RUSSELL, CD ^{[1
]}

CASH, AG ^{[1
]}

机构：

[1] UNIV ALABAMA HOSP,BIRMINGHAM,AL 35233

来源：

INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES | 1979年 / 30卷 / 08期

关键词：

D O I：

10.1016/0020-708X(79)90035-8

中图分类号：

TL [原子能技术]; O571 [原子核物理学];

学科分类号：

0827 ; 082701 ;

摘要：

The reduction of TcO4- in media containing pyrophosphate, methylenediphosphonate, and ethane-1,hydroxyl,-1,1,diphosphonate was studied by amperometric titration with Sn(II). Linear titration curves with single endpoints were observed; from these the oxidation state of the product could be determined without ambiguity. Measurements in acidic, neutral and alkaline media showed that the product of reaction was Tc(IV) except in the case of EHDP, for which the product in neutral or alkaline media was Tc(V). The method appears generally useful for identifying the oxidation state of technetium in radiopharmaceuticals prepared by reduction with Sn(II) or other fast-acting reductants. © 1979.

引用

页码：485 / 488

页数：4

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