PAMAMYCIN - NEW ANTIBIOTIC AND STIMULATOR OF AERIAL MYCELIA FORMATION

被引:80
作者
MCCANN, PA [1 ]
POGELL, BM [1 ]
机构
[1] ST LOUIS UNIV, SCH MED, DEPT MICROBIOL, ST LOUIS, MO 63104 USA
关键词
D O I
10.7164/antibiotics.32.673
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Pamamycin is a new antibiotic isolated from Streptomyces alboniger ATCC 12461. The antibiotic is active in vitro against Gram-positive bacteria, Neurospora, and Mycobacteria. The compound also acts as a streptomycete differentiation effector. It stimulates aerial mycelia formation in the producing organism. The new antibiotic of elemental composition C36H63NO7 is completely different from puromycin, also produced by this strain. The present communication deals with the isolation, properties, and preliminary characterization of pamamycin. © 1979, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.
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页码:673 / 678
页数:6
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