SYNTHESIS AND DIURETIC ACTIVITY OF IMIDAZO[2,1-B]THIAZOLE ACETOHYDRAZONES

被引：81

作者：

ANDREANI, A ^{[1
]}

RAMBALDI, M ^{[1
]}

MASCELLANI, G ^{[1
]}

RUGARLI, P ^{[1
]}

机构：

[1] MEDIOLANUM FARMACEUT SRL, Milan, ITALY

来源：

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 1987年 / 22卷 / 01期

关键词：

D O I：

10.1016/0223-5234(87)90169-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The synthesis of dimethylaminoacetohydrazones of 5-formylimidazo[2,1-b]thiazoles and thiazolines is reported. A potent diuretic activity was confirmed for the 2-methyl derivative bearing a phenyl ring at position 6 (41).

引用

页码：19 / 22

页数：4

共 10 条

[1] POTENTIAL ANTI-TUMOR AGENTS .7. 5-SUBSTITUTED 6-PHENYLIMIDAZO[2,1-B]THIAZOLES
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[J]. ARCHIV DER PHARMAZIE, 1982, 315 (05) : 451 - 456
[2] ANDREANI A, 1980, FARMACO-ED SCI, V35, P573
[3] CATTO A, 1983, FARMACO-ED SCI, V38, P559
[4] CRAGOE EJ, 1983, DIURETICS CHEM PHARM, P425
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[9] Tajana A, 1979, Boll Chim Farm, V118, P397
[10] SYNTHESES AND ANTI-INFLAMMATORY ACTIVITIES OF SUBSTITUTED ARYLAMINO-[N'-BENZYLIDENE)ACETOHYDRAZIDES AND DERIVATIVES
VERMA, M
GUJRATI, VR
SHARMA, M
BHALLA, TN
SAXENA, AK
SINHA, JN
BHARGAVA, KP
SHANKER, K
[J]. ARCHIV DER PHARMAZIE, 1984, 317 (10) : 890 - 894

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