4,5-SECO-4,6-CYCLOSTEROIDS .I. STRUCTURE AND PROPERTIES OF DIOL FROM REDUCTIVE REARRANGEMENT OF 6BETA-BROMO-4BETA,5-EPOXY-5BETA-CHOLESTAN-3BETA-OL

被引：8

作者：

COLLINS, DJ

HOBBS, JJ

RAWSON, RJ

机构：

[1] Department of Veterinary Physiology, University of Sydney, NSW

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 1969年 / 22卷 / 03期

关键词：

D O I：

10.1071/CH9690607

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Treatment of 6β-bromo-4β,5-epoxy-5β-cholestan-3β-Ol (IV) with lithium aluminium hydride in tetrahydrofuran at reflux for 16 hr gave a high yield of a new diol, C27H48O2, formulated as 4,5-seco-4,6-cyolo-6β-cholestane-3β,5α-diol (VIIa). This assignment follows from mechanistic considerations, and the chemical and physical properties of the dial and its transformation products. Stepwise removal of the oxygen functions gave the new hydrocarbon 4,5-seco-4,6-cyclo-6β-cholestane (XIXg). © 1969, CSIRO. All rights reserved.

引用

页码：607 / +

页数：1

共 33 条

[1]

BARTON DHR, 1955, J CHEM SOC, P2056

[2] THE STEREOCHEMISTRY OF CYCLOHEXANE DERIVATIVES [J].