COMPLEMENT-MEDIATED BINDING OF IMMUNOGLOBULINS TO SOME ENDOCRINE-CELLS OF THE PANCREAS AND GUT

被引：25

作者：

BUFFA, R

SOLCIA, E

FIOCCA, R

CRIVELLI, O

PERA, A

机构：

[1] UNIV PAVIA, CTR HISTOPATHOL HISTOCHEM & ULTRASTRUCT, I-27100 PAVIA, ITALY

[2] UNIV PAVIA, INST PATHOL ANAT, I-27100 PAVIA, ITALY

[3] OSPED MAURIZIANO, DIV GASTROENTEROL, TORINO, ITALY

来源：

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY | 1979年 / 27卷 / 09期

关键词：

D O I：

10.1177/27.9.479571

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Unspecific binding of immunoglobulins to gastrin, somatostatin and glucagon cells of the gastrointestinal mucosa or pancreas has been found to occur through a nonantigen-antibody mechanism mediated by the C(1q)fraction of complement. The phenomenon represents an important drawback in hormone immunohistochemistry, which can be overcome by using complement deprived, highly dilute anti-hormone sera.

引用

页码：1279 / 1280

页数：2

共 6 条

[1] BUFFA R, HISTOCHEMISTRY
[2] FACTORS AFFECTING PROPERTIES OF INSOLUBILIZED ANTIBODIES
COMOGLIO, S
MASSAGLIA, A
ROLLERI, E
ROSA, U
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1976, 420 (02) : 246 - 257
[3] STUDIES ON ANTIBODY PRODUCTION .1. A METHOD FOR THE HISTOCHEMICAL DEMONSTRATION OF SPECIFIC ANTIBODY AND ITS APPLICATION TO A STUDY OF THE HYPERIMMUNE RABBIT
COONS, AH
LEDUC, EH
CONNOLLY, JM
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1955, 102 (01) : 49 - +
[4] BIFUNCTIONAL REAGENTS AS VAPOR-PHASE AND LIQUID-PHASE FIXATIVES FOR IMMUNOHISTOCHEMISTRY
PEARSE, AGE
POLAK, JM
[J]. HISTOCHEMICAL JOURNAL, 1975, 7 (02): : 179 - 186
[5] BINDING OF HUMAN IMMUNOGLOBULINS TO PITUITARY ACTH CELLS
POUPLARD, A
BOTTAZZO, GF
DONIACH, D
ROITT, IM
[J]. NATURE, 1976, 261 (5556) : 142 - 144
[6] STERNBERGER LA, 1974, IMMUNOCYTOCHEMISTRY

← 1 →