EVALUATION OF 3BETA-HYDROXY-5BETA-CHOLEST-7-EN-6-ONE AND RELATED STEROIDS AS PRECURSORS OF ECDYSTEROIDS IN CALLIPHORA-STYGIA

被引：6

作者：

FAUX, AF

HORN, DHS

KINNEAR, JF

MARTIN, MD

WILKIE, JS

WILLING, RI

机构：

[1] MELBOURNE STATE COLL,DEPT BIOL,CARLTON,VICTORIA,AUSTRALIA

[2] TOORAK STATE COLL,MALVERN 3144,VICTORIA,AUSTRALIA

来源：

INSECT BIOCHEMISTRY | 1979年 / 9卷 / 01期

关键词：

3β-Hydroxy-5β-cholest-7-en-6-one. 5β-cholest-7-en-3β-ol. 5β-cholest-8(14)-en-3β-ol; Calliphora stygia; ecdysteroids; precursors;

D O I：

10.1016/0020-1790(79)90033-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

3β-Hydroxy-5β-(11,12-3H2)-cholest-7-en-6 -one (15) is incorporated into 20-hydroxyecdysone in Calliphora stygia to the extent of only 0.003% and thus 3β-hydroxy-5β-cholest-7-en-6-one (2) may not be a major precursor of ecdysteroids in this species. The higher incorporation of 3β-hydroxy-5β-(3α-3H)-cholest-7-en-6-one (1) found earlier, appears to be due to compartmentalized transfer of tritium to 3-ketosteroid precursors of 20-hydroxyecdysone. 5β-(11,12-3H2)-Cholest-7-en-3β-ol (13) and 5β(11,12-3H2)-Cholest-8(14)-en-3β-ol (17) are also not incorporated to a significant extent. © 1979.

引用

页码：101 / 105

页数：5

共 16 条

[1]

BHACCA NS, 1966, APPLICATIONS NMR SPE, P86

[2] INVITRO METABOLISM OF 3BETA-HYDROXY-[3ALPHA-H-3]-5BETA-CHOLEST-7-EN-6-ONE, AND 3BETA,14ALPHA-DIHYDROXY-[3ALPHA-H-3]-5BETA-CHOLEST-7-EN-6-ONE BY PROTHORACIC GLANDS OF MANDUCA-SEXTA [J].