SURVIVAL OF CADAVERIC RENAL-TRANSPLANT GRAFTS FROM YOUNG DONORS AND IN YOUNG RECIPIENTS

被引:51
作者
ARBUS, GS
ROCHON, J
THOMPSON, D
机构
[1] Division of Nephrology, Department of Pediatrics, The Hospital for Sick Children, Toronto, M5G 1X8, Ontario
[2] Department of Epidemilology and Biostatistics, University of Western Ontario, London, Ontario
[3] Department of Pediatrics, University of Toronto, Toronto, M5G 1X8, Ontario
关键词
CADAVERIC RENAL TRANSPLANT; YOUNG DONOR; YOUNG RECIPIENT; RENAL THROMBOSIS; ISCHEMIA; TECHNICAL PROBLEMS;
D O I
10.1007/BF00852874
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Evidence from multicenter registries has suggested that cadaveric renal graft survival is poorer when either the recipient or the donor is very young. We therefore analyzed our results from a single pediatric center. There was a significant correlation between greater recipient age and improved cadaveric graft (P = 0.002) and patient (P = 0.0009) survival. The age of the donor also appeared important, particularly in very young children, but became less so as donor age rose. Forty-four percent of recipients under 3 years old who received cadaveric kidneys from donors less than 4 years old lost their grafts as a result of renal thrombosis, ischemia, or technical problems, compared with only 3% of recipients over 9 years of age, whose grafts came from donors who were also over 9 years. The 1-year first cadaveric graft survival rates for these two age groups were 33% and 82% respectively. Our experience confirms the poor findings reported in very young recipients and with very young donors.
引用
收藏
页码:152 / 157
页数:6
相关论文
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