OPTIMIZATION OF A COMMERCIAL LIQUID-CHROMATOGRAPHY MASS-SPECTROMETRY INTERFACE BY STATISTICAL EXPERIMENTAL-DESIGN

被引：8

作者：

HUANG, SK

GLANCY, SB

STANSBURY, WF

机构：

[1] Hoechst Celanese Corp, Corpus Christi, Texas, 78469

来源：

RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 1993年 / 7卷 / 08期

关键词：

D O I：

10.1002/rcm.1290070808

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The efficiency of delivering 4-methoxy phenyl acetic acid particle beam emerging from a commercial liquid chromatography/mass spectrometry interface into the ion source of the mass spectrometer was optimized using response surface modeling (RSM) of the statistical experimental design. It was found that the temperature and pressure of the nebulizer, and the temperature of the desolvation chamber are the major factors for the optimization.

引用

页码：722 / 724

页数：3