SCANNING-TUNNELING-MICROSCOPY OF INSULATORS AND BIOLOGICAL SPECIMENS BASED ON LATERAL CONDUCTIVITY OF ULTRATHIN WATER FILMS

被引：206

作者：

GUCKENBERGER, R ^{[1
]}

HEIM, M ^{[1
]}

CEVC, G ^{[1
]}

KNAPP, HF ^{[1
]}

WIEGRABE, W ^{[1
]}

HILLEBRAND, A ^{[1
]}

机构：

[1] TECH UNIV MUNICH,KLINIKUM RECHTS ISAR,D-81675 MUNICH,GERMANY

来源：

SCIENCE | 1994年 / 266卷 / 5190期

关键词：

D O I：

10.1126/science.7985024

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Scanning tunneling microscopy is based on the flow of an electrical current and thus cannot be used to directly image insulating material. It has been found, however, that a very thin film of water (about one monolayer) adsorbed to a surface exhibits a surprisingly high conductivity that is sufficient to allow scanning tunneling microscope imaging at currents below 1 picoampere. Hydrophilic insulators, such as glass and mica, can thus be imaged in humid air. The same is true for biological specimens deposited on such surfaces, as demonstrated by the scanning tunneling microscope imaging of plasmid DNA on mica.

引用

页码：1538 / 1540

页数：3

共 19 条

[1] INADEQUACY OF LIFSHITZ THEORY FOR THIN LIQUID-FILMS
BEAGLEHOLE, D
RADLINSKA, EZ
NINHAM, BW
CHRISTENSON, HK
[J]. PHYSICAL REVIEW LETTERS, 1991, 66 (16) : 2084 - 2087
[2] MEMBRANE ELECTROSTATICS
CEVC, G
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1990, 1031 (03) : 311 - 382
[3] HYDRATION FORCE MICROSCOPY AS A NEW OPTION FOR STUDIES OF SOLID LIQUID INTERFACES - SOME THEORETICAL CONSIDERATIONS
CEVC, G
KORNYSHEV, AA
[J]. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 1992, 330 (1-2): : 407 - 417
[4] CEVC G, 1993, HYDRATION BIOL MACRO, P338
[5] SCANNING PROBE MICROSCOPY OF COLLAGEN-I AND PN-COLLAGEN-I ASSEMBLIES AND THE RELEVANCE TO SCANNING-TUNNELING-MICROSCOPY CONTRAST GENERATION IN PROTEINS
GATHERCOLE, LJ
MILES, MJ
MCMASTER, TJ
HOLMES, DF
[J]. JOURNAL OF THE CHEMICAL SOCIETY-FARADAY TRANSACTIONS, 1993, 89 (15): : 2589 - 2594
[6] A SCANNING TUNNELING MICROSCOPE (STM) FOR BIOLOGICAL APPLICATIONS - DESIGN AND PERFORMANCE
GUCKENBERGER, R
KOSSLINGER, C
GATZ, R
BREU, H
LEVAI, N
BAUMEISTER, W
[J]. ULTRAMICROSCOPY, 1988, 25 (02) : 111 - 121
[7] SCANNING TUNNELING MICROSCOPY OF A HYDRATED BACTERIAL SURFACE PROTEIN
GUCKENBERGER, R
WIEGRABE, W
HILLEBRAND, A
HARTMANN, T
WANG, ZH
BAUMEISTER, W
[J]. ULTRAMICROSCOPY, 1989, 31 (03) : 327 - 332
[8] IMAGING OF UNCOATED PURPLE MEMBRANE BY SCANNING TUNNELING MICROSCOPY
GUCKENBERGER, R
HACKER, B
HARTMANN, T
SCHEYBANI, T
WANG, Z
WIEGRABE, W
BAUMEISTER, W
[J]. JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B, 1991, 9 (02): : 1227 - 1230
[9] IMAGING OF UNCOATED TOBACCO MOSAIC-VIRUS BY SCANNING-TUNNELING-MICROSCOPY
GUCKENBERGER, R
ARCE, FT
HILLEBRAND, A
HARTMANN, T
[J]. JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B, 1994, 12 (03): : 1508 - 1511
[10] GUCKENBERGER R, UNPUB

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