SYNTHESIS AND USE OF NOVEL CHIRAL SURFACTANTS IN MICELLAR ELECTROKINETIC CAPILLARY CHROMATOGRAPHY

被引：18

作者：

DALTON, DD ^{[1
]}

TAYLOR, DR ^{[1
]}

WATERS, DG ^{[1
]}

机构：

[1] SMITHKLINE BEECHAM PHARMACEUT,TONBRIDGE TN11 9AN,KENT,ENGLAND

来源：

JOURNAL OF CHROMATOGRAPHY A | 1995年 / 712卷 / 02期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/0021-9673(95)00449-W

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This paper presents the synthesis of some novel chiral surfactants based on (R,R)-tartaric acid and long-chain aliphatic amines. Evidence for their ability to form micelles based on surface tension measurements will be given. Several chiral separations have been achieved and these will be presented for one of the surfactants. A discussion of the chiral selectivity data will show a preference for resolving certain compounds of a similar structure. Ideas for further work with these surfactants will be outlined.

引用

页码：365 / 371

页数：7

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