LACK OF IN VITRO REPAIR OF X-RAY-INDUCED CHAIN BREAKS IN DNA BY POLYNUCLEOTIDE-JOINING ENZYME

被引：38

作者：

KAPP, DS

SMITH, KC

机构：

[1] Department of Radiology, Stanford University School of Medicine, Stanford, CA

来源：

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY AND RELATED STUDIES IN PHYSICS CHEMISTRY AND MEDICINE | 1969年 / 14卷 / 06期

关键词：

D O I：

10.1080/09553006914551741

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

The polynucleotide-joining enzyme does not repair (in one step) the single-strand chain breaks produced in DNA by x-irradiation in aqueous media. Preliminary data on the chemical nature of the ends of the broken strands suggest that nuclease action (to 'clean' the termini), followed by polymerase action, is necessary before the irradiated DNA would become a substrate for the polynucleotide-joining enzyme. © 1969 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：567 / &

共 14 条

[1] SEDIMENTATION RATE AS A MEASURE OF MOLECULAR WEIGHT OF DNA
BURGI, E
HERSHEY, AD
[J]. BIOPHYSICAL JOURNAL, 1963, 3 (04) : 309 - &
[2] CHAIN SCISSION AND HYDROGEN BOND BREAKAGE ON IRRADIATION OF DNA
COLLYNS, B
OKADA, S
SCHOLES, G
WEISS, JJ
WHEELER, CM
[J]. RADIATION RESEARCH, 1965, 25 (03) : 526 - &
[3] MECHANISM OF INACTIVATION OF COLIPHAGE T7 BY XRAYS
FREIFELDER, D
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1965, 54 (01) : 128 - +
[4] ENZYMATIC REPAIR OF DNA .I. FORMATION OF CIRCULAR LAMBDADNA
GEFTER, ML
BECKER, A
HURWITZ, J
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1967, 58 (01) : 240 - &
[5] DNA-STRAND SCISSION AND LOSS OF VIABILITY AFTER X IRRADIATION OF NORMAL AND SENSITIZED BACTERIAL CELLS
KAPLAN, HS
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1966, 55 (06) : 1442 - &
[6] Krushinskaya NP, 1967, RADIOBIOLOGY, V7, P36
[7] RECONSTRUCTION IN VIVO OF IRRADIATED ESCHERICHIA COLI DEOXYRIBONUCLEIC ACID REJOINING OF BROKEN PIECES
MCGRATH, RA
WILLIAMS, RW
[J]. NATURE, 1966, 212 (5061) : 534 - &
[8] LINKAGE OF POLYNUCLEOTIDES THROUGH PHOSPHODIESTER BONDS BY AN ENZYME FROM ESCHERICHIA COLI
OLIVERA, BM
LEHMAN, IR
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1967, 57 (05) : 1426 - &
[9] MECHANISM OF THE RADIATION-INDUCED DEGRADATION OF NUCLEIC ACIDS
SCHOLES, G
WARD, JF
WEISS, J
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1960, 2 (06) : 379 - 391
[10] Smith K C, 1966, Photochem Photobiol, V5, P777, DOI 10.1111/j.1751-1097.1966.tb05773.x

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