EEG ELECTRODE SENSITIVITY - AN APPLICATION OF RECIPROCITY

In this paper, the reciprocity theorem is used to determine the sensitivity of EEG leads to the location and orientation of sources in the brain. Quantitative information used in determining the sensitivity is derived from constant potential plots of a three-concentric-sphere mathematical model of the head with current applied through surface leads (the reciprocal problem), and from an electrolytic tank employing a human skull. Advantages of the reciprocal or lead field approach are outlined and the following conclusions are drawn. 1) Leads placed at the end of a diameter through the center of the brain have a range of sensitivity due to source location of only 3 to 1. 2) For the same electrode placement, sensitivity is maximum to sources oriented parallel to the line of the electrodes regardless of source location. 3) Electrodes spaced 5 cm apart are about ten times more sensitive to proximal cortical sources (by virtue of position) than to sources near the center of the brain. In the Appendixes, the solution is derived for the potential and current density in three concentric conducting spheres energized by arbitrarily placed point electrodes on the surface, and the reciprocity theorem is extended to inhomogeneous anisotropic media. Copyright © 1969 by The Institute of Electrical and Electronics Engineers, Inc.