FAST ALGORITHM FOR PEPTIDE SEQUENCING BY MASS-SPECTROSCOPY

被引：102

作者：

BARTELS, C

机构：

[1] Biocentre of the University of Basle, Basle, CH-4056

来源：

BIOMEDICAL AND ENVIRONMENTAL MASS SPECTROMETRY | 1990年 / 19卷 / 06期

关键词：

D O I：

10.1002/bms.1200190607

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

An automatic algorithm for sequencing polypeptides from fast atom bombardment tandem mass spectra is presented. Based on graph theory considerations it finds the most probable sequences, even if the amino acid composition is unknown, by scoring mass differences. The algorithm is fast as the computing time increases by less than the square of the number of amino acids. Pairs of two or three amino acids are proposed to explain the gap if peaks are missing. Copyright © 1990 John Wiley & Sons, Ltd.

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页码：363 / 368

页数：6

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