HIV-RELATED THROMBOCYTOPENIA

被引：4

作者：

BLOCKMANS, D

VERMYLEN, J

机构：

[1] Dienst Inwendige Geneeskunde, Afdeling Bloedings- en Vaatziekten, U.Z. Gasthuisberg, 3000 Leuven

来源：

ACTA CLINICA BELGICA | 1992年 / 47卷 / 02期

关键词：

D O I：

10.1080/17843286.1992.11718217

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

HIV-related chronic ITP is caused by an accelerated platelet destruction due to adsorption of circulating immune complexes and to specific anti-platelet antibodies, but perhaps also by a defective thrombopoiesis resulting from invasion of the megakaryocytes by the retrovirus. Treatment is needed when platelet numbers drop beneath 20.10(9)/Lor when severe bleeding symptoms occur. Steroids, commercially available immunoglobulins for IV use, AZT and anti-Rh immunoglobulins can be administered, although relapses are frequent after withdrawal of the drugs. Recurrences after splenectomy are far less common, but the progression towards AIDS might be accelerated.

引用

页码：117 / 123

页数：7