REMOVING THE HEART FROM THE BRAIN - COMPENSATION FOR THE PULSE ARTIFACT IN THE PHOTON MIGRATION SIGNAL

被引:136
作者
GRATTON, G
CORBALLIS, PM
机构
[1] Department of Psychology, Columbia University, New York
关键词
PHOTON MIGRATION TECHNIQUES; PHOTOPLETHYSMOGRAPHY; REGIONAL CEREBRAL BLOOD FLOW MEASUREMENT;
D O I
10.1111/j.1469-8986.1995.tb02958.x
中图分类号
B84 [心理学];
学科分类号
04 ; 0402 ;
摘要
Various factors, including variations in the concentration of hemoglobin, determine changes in the transparency of living tissue to near-infrared light. Hence, optical measures have been proposed as a noninvasive method for investigating regional changes in brain activity. However, the amount of near-infrared light traversing a region of the head is also influenced by the periodic changes in blood pressure that occur during the cardiac cycle (pulse). These large changes may obscure smaller, localized events associated with brain activity. We developed a least-squares regression algorithm for compensating for the artifact introduced by the pulse. This procedure takes into account beat-to-beat variability in heart rate and differences in the shape of the pulse among subjects and among recording conditions.
引用
收藏
页码:292 / 299
页数:8
相关论文
共 17 条
[1]   FUNCTIONAL MAPPING OF THE HUMAN VISUAL-CORTEX BY MAGNETIC-RESONANCE-IMAGING [J].
BELLIVEAU, JW ;
KENNEDY, DN ;
MCKINSTRY, RC ;
BUCHBINDER, BR ;
WEISSKOFF, RM ;
COHEN, MS ;
VEVEA, JM ;
BRADY, TJ ;
ROSEN, BR .
SCIENCE, 1991, 254 (5032) :716-719
[2]  
Chance B, 1989, PHOTON MIGRATION TIS
[3]   PERSPECTIVES ON COGNITIVE NEUROSCIENCE [J].
CHURCHLAND, PS ;
SEJNOWSKI, TJ .
SCIENCE, 1988, 242 (4879) :741-745
[4]  
CORBALLIS PM, 1994, PSYCHOPHYSIOLOGY S1, V31, pS36
[5]  
FRAHM J, IN PRESS NMR BIOMEDI
[6]  
FROSTIG RD, 1994, CEREB CORTEX, P331
[7]   A NEW METHOD FOR OFF-LINE REMOVAL OF OCULAR ARTIFACT [J].
GRATTON, G ;
COLES, MGH ;
DONCHIN, E .
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1983, 55 (04) :468-484
[8]   FEASIBILITY OF INTRACRANIAL NEAR-INFRARED OPTICAL-SCANNING [J].
GRATTON, G ;
MAIER, JS ;
FABIANI, M ;
MANTULIN, WW ;
GRATTON, E .
PSYCHOPHYSIOLOGY, 1994, 31 (02) :211-215
[9]  
GRATTON G, 1994, UNPUB RAPID CHANGES
[10]   FUNCTIONAL ARCHITECTURE OF CORTEX REVEALED BY OPTICAL IMAGING OF INTRINSIC SIGNALS [J].
GRINVALD, A ;
LIEKE, E ;
FROSTIG, RD ;
GILBERT, CD ;
WIESEL, TN .
NATURE, 1986, 324 (6095) :361-364