GI ABSORPTION OF BETA-LACTAM ANTIBIOTICS .2. DEVIATION FROM PH-PARTITION HYPOTHESIS IN PENICILLIN ABSORPTION THROUGH INSITU AND INVITRO LIPOIDAL BARRIERS

被引：35

作者：

TSUJI, A ^{[1
]}

MIYAMOTO, E ^{[1
]}

HASHIMOTO, N ^{[1
]}

YAMANA, T ^{[1
]}

机构：

[1] KANAZAWA UNIV,FAC PHARMACEUT SCI,KANAZAWA,ISHIKAWA 920,JAPAN

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1978年 / 67卷 / 12期

关键词：

D O I：

10.1002/jps.2600671219

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1705 / 1711

页数：7

共 37 条

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[5] DRUG ABSORPTION .4. INFLUENCE OF PH ON ABSORPTION KINETICS OF WEAKLY ACIDIC DRUGS [J].

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DOLUISIO, JT .

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[6] DRUG ABSORPTION .I. AN IN SITU RAT GUT TECHNIQUE YIELDING REALISTIC ABSORPTION RATES [J].

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[7] NEW SUBSTITUENT CONSTANT PI DERIVED FROM PARTITION COEFFICIENTS [J].

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[8]

FURUSAWA S, 1971, J PHARM PHARMACOL, V24, P272

[9]

Glasstone S, 1941, THEORY RATE PROCESSE

[10] THEORETICAL MODEL STUDIES OF INTESTINAL DRUG ABSORPTION .4. BILE-ACID TRANSPORT AT PREMICELLAR CONCENTRATIONS ACROSS DIFFUSION LAYER-MEMBRANE BARRIER [J].

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