GAMMA-DELTA SEQUENCE OF F IS AN INSERTION SEQUENCE

被引：307

作者：

GUYER, MS

机构：

[1] Laboratory of Molecular Biology National Institute of Arthritis, Metabolism and Digestive Diseases, National Institutes of Health, Bethesda

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1978年 / 126卷 / 03期

关键词：

D O I：

10.1016/0022-2836(78)90045-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The F plasmid is able to co-transfer (mobilize) the small, chimeric R plasmid pBR322 during conjugation only at a very low frequency (Bolivar et al., 1977). Mobilization has been found here to be invariably (> 99%) associated with a structural alteration of pBR322. The alteration was shown, by restriction endonuclease analysis and electron microscopy, to be an insertion of the F attachment sequence λδ (2.8 to 8.5F). λδ is, therefore, an insertion sequence. © 1978.

引用

页码：347 / 365

页数：19

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