PYRUVATE ALDOLASES AS REAGENTS FOR STEREOSPECIFIC ALDOL CONDENSATION

被引：26

作者：

ALLEN, ST ^{[1
]}

HEINTZELMAN, GR ^{[1
]}

TOONE, EJ ^{[1
]}

机构：

[1] DUKE UNIV,DEPT CHEM,DURHAM,NC 27706

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 02期

关键词：

D O I：

10.1021/jo00028a005

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

KDPG aldolase, a representative member of the largest but as of yet unexplored group of aldolases which utilize pyruvate as the nucleophilic component in aldol condensation, accepts a number of unnatural aldehydes as electrophiles in stereospecific aldol condensation, providing access to highly and differentially functionalized alpha-keto acid products.

引用

页码：426 / 427

页数：2

共 16 条

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