HUMAN PROVIRAL MESSENGER-RNAS DOWN REGULATED IN CHORIOCARCINOMA ENCODE A ZINC FINGER PROTEIN RELATED TO KRUPPEL

被引：71

作者：

KATO, N

SHIMOTOHNO, K

VANLEEUWEN, D

COHEN, M

机构：

[1] ABBOTT LABS,DEPT MOLEC BIOL,D93D,AP20-5,N CHICAGO,IL 60064

[2] NATL CANC CTR,RES INST,DIV VIROL,CHUO KU,TOKYO 104,JAPAN

来源：

MOLECULAR AND CELLULAR BIOLOGY | 1990年 / 10卷 / 08期

关键词：

D O I：

10.1128/MCB.10.8.4401

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

RNA transcripts of the HERV-R (ERV3) human provirus that are abundant in placenta but absent in choriocarcinoma contain nonproviral genomic sequences at their 3′ ends. We report here the isolation of cDNA clones of these genomic sequences. The transcripts encode a Krüppel-related zinc finger protein consisting of a unique leader region and more than 12 28-amino-acid finger motifs.

引用

页码：4401 / 4405

页数：5

共 25 条

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