C-glycosylflavones from the leaves of Iris tectorum Maxim

被引：17

作者：

Ma, Yuhan ^{[1
,2
,3
]}

Li, Huan ^{[4
]}

Lin, Binbin ^{[1
,2
]}

Wang, Guokai ^{[1
,2
]}

Qin, Minjian ^{[1
,2
]}

机构：

[1] China Pharmaceut Univ, Dep Resources Sci Tradit Chinese Med, Nanjing 210009, Jiangsu, Peoples R China

[2] China Pharmaceut Univ, State Key Lab Nat Med, Nanjing 210009, Jiangsu, Peoples R China

[3] Jiangsu Honghui Med Com Ltd, R&D Dept, Nanjing 210009, Jiangsu, Peoples R China

[4] North China Petr Adm Bur, Gen Hosp, Dept Gen Surg, Renqiu 062552, Peoples R China

来源：

ACTA PHARMACEUTICA SINICA B | 2012年 / 2卷 / 06期

基金：

中国国家自然科学基金;

关键词：

Iris tectorum; Iridaceae; C-glycosylflavones; Cytotoxic activities;

D O I：

10.1016/j.apsb.2012.10.007

中图分类号：

R9 [药学];

学科分类号：

1007 [药学];

摘要：

A new C-glycosylflavone, 5-hydroxy1-4',7-dimethoxyflavone-6-C-[O-(alpha-L-3"'-acetylrhamnopyranosyl)-1 -> 2-beta-D-glucopyranoside] (1), along with five known C-glycosylflavones, 5-hydroxy-4',7-dimethoxyflavone-6-C-[O-(alpha-L-2"'-acetylrhamnopyranosyl)-1 -> 2-beta-D-glucopyranoside] (2), embinin (3), embigenin (4), swertisin (5) and swertiajaponin (6) were isolated from the leaves of Iris tectorum Maxim. Their structures were elucidated on the basis of extensive NMR experiments and spectral methods and their cytotoxic activities against A549 (lung cancer) human cell lines were determined. (C) 2012 Institute of Materia Medica, Chinese Academy of Medical Sciences and Chinese Pharmaceutical Association. Production and hosting by Elsevier B.V. All rights reserved.

引用

页码：598 / 601

页数：4

共 19 条

[1]

C-glycosylanthocyanidins synthesized from C-glycosylflavones [J].