THE TOTAL SYNTHESIS OF NANNOCHELIN - A NOVEL CINNAMOYL HYDROXAMATE-CONTAINING SIDEROPHORE

被引：35

作者：

BERGERON, RJ

PHANSTIEL, O

机构：

[1] Department of Medicinal Chemistry, University of Florida, J. Hillis Miller Health Center, Gainesville

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 26期

关键词：

D O I：

10.1021/jo00052a030

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The total synthesis of nannochelin A, a siderophore isolated from Nannocystis exedens, is described. The key transformation involves the tandem oxidation-acylation of the N(epsilon)-amino group of N(alpha)-BOC-L-lysine methyl ester prior to coupling with the external carboxyls of citric acid.

引用

页码：7140 / 7143

页数：4

共 18 条

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