SYMPATHETIC NERVOUS-SYSTEM MODULATES MACROPHAGE FUNCTION

被引：33

作者：

CHELMICKASCHORR, E

KWASNIEWSKI, MN

CZLONKOWSKA, A

机构：

[1] UNIV CHICAGO,DEPT PEDIAT,CHICAGO,IL 60637

[2] UNIV CHICAGO,INST BRAIN RES,CHICAGO,IL 60637

来源：

INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY | 1992年 / 14卷 / 05期

关键词：

D O I：

10.1016/0192-0561(92)90082-V

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We have reported previously that sympathectomy augments immune response in mice and rats. In the present study, we show that ablation of the sympathetic nervous system augments macrophage function as measured by increased TNF secretion. We also show that a factor present in the sympathetic ganglia of newborn rats, suppresses secretion of TNF by LPS-stimulated macrophages as does the beta-adrenergic agonist isoproterenol.

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收藏

页码：841 / 846

页数：6

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