NEUROLOGICAL SOFT SIGNS IN SCHIZOPHRENIA

被引：208

作者：

SCHRODER, J

NIETHAMMER, R

GEIDER, FJ

REITZ, C

BINKERT, M

JAUSS, M

SAUER, H

机构：

[1] Department of Psychiatry, University of Heidelberg, D-6900 Heidelberg

来源：

SCHIZOPHRENIA RESEARCH | 1991年 / 6卷 / 01期

关键词：

NEUROLOGICAL SOFT SIGN; MOTOR COORDINATION; BRAIN ALTERATION; BASAL GANGLIA; (SCHIZOPHRENIA);

D O I：

10.1016/0920-9964(91)90017-L

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

A new scale for neurological soft signs (NSS) was constructed and consists of 17 items compiled from the literature. The scale was found to have a high internal reliability (Cronbach's alpha 0.83) and a high interrater reliability (0.88). According to the results of a factor analysis, NSS are covered by five factors: 'motor coordination', 'integrative functions', 'complex motor tasks', 'right/left and spatial orientation' and 'hard signs'. Using this scale, the associations of NSS with clinical course and brain alterations were investigated. NSS varied with the clinical course and were significantly correlated with some BPRS subscales, in particular 'thought disorder'. In addition, the 'motor coordination' soft signs were found to correlate with morphological alterations in the basal ganglia.

引用

页码：25 / 30

页数：6

共 15 条

[1]

BATES B, 1983, GUIDE PHYSICAL EXAMI

[2] NEUROLOGICAL SOFT SIGNS AND PSYCHOPATHOLOGY .1. FINDINGS IN SCHIZOPHRENIA [J].