SELENIUM LOSSES IN 10 BURNED PATIENTS

被引：48

作者：

BERGER, MM

CAVADINI, C

BART, A

BLONDEL, A

BARTHOLDI, I

VANDERVALE, A

KRUPP, S

CHIOLERO, R

FREEMAN, J

DIRREN, H

机构：

[1] Anesthesiology, Centre Hospitalier Universitaire Vaudios (CHUV)

[2] Nestlé Research Centre, NESTEC SA

[3] Burns Centre and Plastic Surgery, CHUV

来源：

CLINICAL NUTRITION | 1992年 / 11卷 / 02期

关键词：

D O I：

10.1016/0261-5614(92)90014-H

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

To determine the selenium (Se) losses and balances, 10 patients with burns of 32 +/- 9% (mean +/- SD) of total body surface and aged 36 +/- 9 years were studied from D1 (first post-injury) until D7. Cutaneous losses were extracted from the textiles surrounding the patients. Serum and urine were collected until D20. Exudative losses of nitrogen decreased progressively (mean 8.7 +/- 3.8 g/24H). Se was detectable in wound seepage only during excision-grafting: mean operative loss was 342 +/- 191-mu-g. Mean urinary Se excretion was 41 +/- 13-mu-g/24H. Operative cutaneous losses led to some negative balances. Serum Se and glutathione peroxydase (GSHPx) were depressed until D20. Serum Se was related to N intake (p < 0.001). The decrease Se and GSHPx levels reflect a deficiency state, which measured losses did not explain, but limitations of the measurement methods prevented detection of Se cutaneous losses less-than-or-equal-to 100-mu-g/24H.

引用

页码：75 / 82

页数：8

共 31 条

[1] Jahoor, Desai, Herndon, Wolfe, Dynamics of the protein metabolic response to burn injury, Metabolism, 37, pp. 330-337, (1988)
[2] Wilmore, Aulick, Metabolic changes in burned patients, Surgical Clinics of North America, 58, pp. 1173-1187, (1978)
[3] Hesselvik, Carlsson, von Schenck, Sorbo, Low selenium plasma levels in surgical and intensive care patients: relation to infection, Clinical Nutrition, 6, pp. 279-283, (1987)
[4] Chen, Yang, Chen, Et al., Studies on the relations of selenium and Keshan disease, Biological Trace Element Research, 2, pp. 91-107, (1980)
[5] Fleming, McCall, O'Brien, Et al., Selenium status in patients receiving home parenteral nutrition, Journal of Parenteral and Enteral Nutrition, 8, pp. 258-262, (1984)
[6] Levander, Clinical consequences of low selenium intake and its relationship to vitamin E, Annals of the New York Academy of Sciences, 383, pp. 70-82, (1982)
[7] Quercia, Korn, O'Neill, Et al., Selenium deficiency and fatal cardiomyopathy in a patient receiving long-term home parenteral nutrition, Clinical Pharmacology, 3, pp. 531-535, (1984)
[8] Kien, Ganther, Manifestations of chronic selenium deficiency in a child receiving total parenteral nutrition, American Journal of Clinical Nutrition, 37, pp. 319-328, (1983)
[9] Mansell, Allison, Shenkin, Reversal
[10] of skeletal myopathy with selenium supplementation in a patient on home parenteral nutrition, Clinical Nutrition, 5, (1986)

← 1 2 3 4 →