POSTVACCINAL PARKINSONISM

被引:30
作者
ALVES, RSC [1 ]
BARBOSA, ER [1 ]
SCAFF, M [1 ]
机构
[1] UNIV SAO PAULO,GEN HOSP,DEPT NEUROL,SAO PAULO,BRAZIL
关键词
ENCEPHALITIS; RIGID-AKINETIC SYNDROME; PARKINSONISM;
D O I
10.1002/mds.870070213
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
A 5-year-old boy, with a history of fever beginning 15 days after a vaccination for measles, developed a rigid-akinetic syndrome 3 days after the fever began. A spinal tap obtained 1 week after the onset of fever showed pleocytosis with a monocellular pattern. A CT scan of the head and EEG did not disclose any abnormality. An MRI performed 3 months after the event, however, showed clear-cut evidence of bilateral substantia nigra lesions, suggesting secondary gliosis. The response to levodopa was good, but adverse reactions appeared early. The child is now 7 years old. Bromocriptine, deprenyl, and levodopa have produced a remarkable improvement of the parkinsonian features.
引用
收藏
页码:178 / 180
页数:3
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