ASSIGNMENT OF PROTEIN NMR-SPECTRA IN THE LIGHT OF HOMONUCLEAR 3D SPECTROSCOPY - AN AUTOMATABLE PROCEDURE BASED ON 3D TOCSY-TOCSY AND 3D TOCSY-NOESY

被引：27

作者：

OSCHKINAT, H

HOLAK, TA

CIESLAR, C

机构：

[1] Max-Planck Institut Für Biochemie, München

来源：

BIOPOLYMERS | 1991年 / 31卷 / 06期

关键词：

D O I：

10.1002/bip.360310615

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Automated assignment of proteins is greatly simplified using data from 3D-nmr spectra. A strategy is presented which makes use of 3D-TOCSY-TOCSY and 3D-TOCSY-NOESY; its potential is demonstrated with the example of the spectra of BPTI. The discussion of the potential of 3D-nmr includes the introduction of a simple graph for the description of the information content of multidimensional nmr spectra.

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页码：699 / 712

页数：14

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