COMPLETE NUCLEOTIDE-SEQUENCE OF SACCHAROMYCES-CEREVISIAE CHROMOSOME-VIII

被引：258

作者：

JOHNSTON, M ^{[1
]}

ANDREWS, S ^{[1
]}

BRINKMAN, R ^{[1
]}

COOPER, J ^{[1
]}

DING, H ^{[1
]}

DOVER, J ^{[1
]}

DU, Z ^{[1
]}

FAVELLO, A ^{[1
]}

FULTON, L ^{[1
]}

GATTUNG, S ^{[1
]}

GEISEL, C ^{[1
]}

KIRSTEN, J ^{[1
]}

KUCABA, T ^{[1
]}

HILLIER, L ^{[1
]}

JIER, M ^{[1
]}

JOHNSTON, L ^{[1
]}

LANGSTON, Y ^{[1
]}

LATREILLE, P ^{[1
]}

LOUIS, EJ ^{[1
]}

MACRI, C ^{[1
]}

MARDIS, E ^{[1
]}

MENEZES, S ^{[1
]}

MOUSER, L ^{[1
]}

NHAN, M ^{[1
]}

RIFKIN, L ^{[1
]}

RILES, L ^{[1
]}

STPETER, H ^{[1
]}

TREVASKIS, E ^{[1
]}

VAUGHAN, K ^{[1
]}

VIGNATI, D ^{[1
]}

WILCOX, L ^{[1
]}

WOHLDMAN, P ^{[1
]}

WATERSTON, R ^{[1
]}

WILSON, R ^{[1
]}

VAUDIN, M ^{[1
]}

机构：

[1] WASHINGTON UNIV,SCH MED,DEPT GENET,ST LOUIS,MO 63110

来源：

SCIENCE | 1994年 / 265卷 / 5181期

关键词：

D O I：

10.1126/science.8091229

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII reveals that it contains 269 predicted or known genes (300 base pairs or larger). Fifty-nine of these genes (22 percent) were previously identified. Of the 210 novel genes, 65 are predicted to encode proteins that are similar to other proteins of known or predicted function. Sixteen genes appear to be relatively recently duplicated. On average, there is one gene approximately every 2 kilobases. Although the coding density and base composition across the chromosome are not uniform, no regular pattern of variation is apparent.

引用

页码：2077 / 2082

页数：6

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