LASER CONIZATION - THE RESULTS OF TREATMENT OF CERVICAL INTRAEPITHELIAL NEOPLASIA

被引:37
作者
ANDERSEN, ES [1 ]
PEDERSEN, B [1 ]
NIELSEN, K [1 ]
机构
[1] AALBORG HOSP,DEPT PATHOL,DK-9000 AALBORG,DENMARK
关键词
D O I
10.1006/gyno.1994.1193
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Combination laser conization was performed for the treatment of cervical intraepithelial neoplasia (CIN) in 473 patients, who were followed for a mean period of 70 months. In 16 cases (3.4%) CIN was demonstrated during follow up, and in 10 cases (2.1%) within the first year after treatment. The grade of CIN in the cone specimen was of no predictive value to recurrence. When excisional margins were involved recurrence was observed in 8.7% of cases, compared to 2.3% when margins were uninvolved. The risk of recurrence was significantly higher in patients with involvement of the endocervical cone margin. The only case of invasive disease during follow-up was observed more than 2 years after conization; cone biopsy was without involved margins. The results clearly demonstrate the method to be effective and justify an expectant management of all patients after conization by this method. (C) 1994 Academic Press, Inc.
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页码:201 / 204
页数:4
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