INTELLIGENT AUTOMATED CORRECTION OF BASEPLANE AND SYSTEMATIC NOISE IN 2-DIMENSIONAL NMR-SPECTRA

A computer program useful for 2D NMR data is described that provides automatic two-dimensional baseplane correction and subsequent tl and fl ridge suppression. The algorithm per forms combined correction of smooth baseplane distortions and sharp ridges in 2D NMR spectra through five steps: (1) identification of resonance peaks and ridges, (2) extraction of initial, putative global baseplane, (3) window filtering of the corresponding time domain, (4) construction of a 2D spectrum free of baseplane distortion, and (5) suppression of ridges, The optimal parameters for baseplane and ridge correction are automatically decided by the program, yielding a greatly improved spectrum, together with more accurate spectral information. (C) 1994 Academic Press, Inc.