DOSE-DEPENDENT HYPOLIPIDEMIC EFFECT OF AN INHIBITOR OF HMG-COA REDUCTASE, PRAVASTATIN (CS-514), IN HYPERCHOLESTEROLEMIC SUBJECTS - A DOUBLE BLIND TEST

被引：47

作者：

SAITO, Y

GOTO, Y

NAKAYA, N

HATA, Y

HOMMA, Y

NAITO, C

HAYASHI, H

ITO, H

YAMAMOTO, M

TAKEUCHI, I

MORI, K

HARA, T

YOSHIDA, S

SHIRAI, K

SASAKI, N

SHINOMIYA, M

MURANO, S

MORISAKI, N

NISHIIDE, T

KANZAKI, T

WATANABE, N

ISHIKAWA, T

机构：

[1] TOKAI UNIV,SCH MED,DEPT INTERNAL MED 1,ISEHARA,KANAGAWA 25911,JAPAN

[2] KEIO UNIV,SCH MED,DEPT INTERNAL MED,TOKYO 108,JAPAN

[3] TOKYO TEISHIN HOSP,DEPT INTERNAL MED,TOKYO,JAPAN

[4] TOKYO METROPOLITAN OHKUBO GEN HOSP,DEPT INTERNAL MED,TOKYO,JAPAN

[5] TACHIKAWA KOYOSAI HOSP,DEPT INTERNAL MED,TACHIKAWA,JAPAN

[6] GEN OTA HOSP,DEPT INTERNAL MED,OTA,JAPAN

[7] JIKEI UNIV SCH MED,AOTO HOSP,DEPT INTERNAL MED,TOKYO 105,JAPAN

来源：

ATHEROSCLEROSIS | 1988年 / 72卷 / 2-3期

关键词：

D O I：

10.1016/0021-9150(88)90082-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：205 / 211

页数：7

共 23 条

[1]

ALBERTS AW, 1980, P NATL ACAD SCI USA, V77, P3597

[2]

ALLAIN CC, 1974, CLIN CHEM, V20, P470

[3] MEVINOLIN AND COLESTIPOL STIMULATE RECEPTOR-MEDIATED CLEARANCE OF LOW-DENSITY LIPOPROTEIN FROM PLASMA IN FAMILIAL HYPERCHOLESTEROLEMIA HETEROZYGOTES [J].

BILHEIMER, DW ;

GRUNDY, SM ;

BROWN, MS ;

GOLDSTEIN, JL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (13) :4124-4128

[4]

Burnstein M, 1970, J LIPID RES, V11, P583

[5] COMPETITIVE INHIBITION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE BY ML-236A AND ML-236B FUNGAL METABOLITES, HAVING HYPOCHOLESTEROLEMIC ACTIVITY [J].

ENDO, A ;

KURODA, M ;

TANZAWA, K .

FEBS LETTERS, 1976, 72 (02) :323-326

[6]

FRIEDEWALD WT, 1972, CLIN CHEM, V18, P499

[7]

GOLDSTEIN JL, 1979, J BIOL CHEM, V254, P5403

[8] PREDISPOSITION TO ATHEROSCLEROSIS IN HEAD, HEART, AND LEGS - FRAMINGHAM STUDY [J].

GORDON, T ;

KANNEL, WB .

JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1972, 221 (07) :661-&

[9]

GOTO Y, 1986, J CLIN BIOCHEM NUTR, V1, P73

[10] TREATMENT OF HYPERCHOLESTEROLEMIA [J].

GRUNDY, SM .

AMERICAN JOURNAL OF CLINICAL NUTRITION, 1977, 30 (06) :985-992

← 1 2 3 →