A USEFUL REAGENT FOR DERIVATIZATION OF AMINO-ACIDS

被引：16

作者：

ALLENMARK, S

机构：

[1] Laboratory of Microbiological Chemistry, University of Gothenburg, S-41346 Gothenburg

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 10期

关键词：

D O I：

10.1016/S0040-4039(00)88831-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-(Chloroformyl)-carbazole, which is readily synthesized by phosgenation of carbazole, has been shown to be an excellent reagent for fluorogenic labelling of amino acids. The dearivatization reaction is carried out at room temperature in a borate buffer of pH 9 and yields highly fluorescent derivatives with good chromatographic properties. Further, the derivatives of amino acid enantiomers are well separated on BSA-silica (Resolvosil®) analytical columns. © 1990.

引用

页码：1455 / 1458

页数：4

共 18 条

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