RECEPTORS FOR TRANSFERRIN IN PATHOGENIC BACTERIA ARE SPECIFIC FOR THE HOSTS PROTEIN

被引：77

作者：

SCHRYVERS, AB

GONZALEZ, GC

机构：

来源：

CANADIAN JOURNAL OF MICROBIOLOGY | 1990年 / 36卷 / 02期

关键词：

Iron; Receptor; Transferrin;

D O I：

10.1139/m90-026

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Transferrin receptors detected by a solid-phase binding assay were shown to be specific for the host's transferrin in the representative bacterial pathogens Neisseria meningitidis (human), Pasteurella haemolytica (bovine), and Actinobacillus pleuropneumoniae (porcine). Consistent with the receptor specificity, iron-deficient bacteria were only capable of utilizing transferrin from the host as a source of iron for growth.

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页码：145 / 147

页数：3

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