PHYSICIAN ATTITUDES ABOUT ANTICOAGULATION FOR NONVALVULAR ATRIAL-FIBRILLATION IN THE ELDERLY

被引:207
作者
MCCRORY, DC
MATCHAR, DB
SAMSA, G
SANDERS, LL
PRITCHETT, ELC
机构
[1] DUKE UNIV,MED CTR,DEPT MED,DIV GEN INTERNAL MED,DURHAM,NC 27710
[2] DUKE UNIV,MED CTR,DEPT MED,DIV CARDIOL,DURHAM,NC 27710
[3] DUKE UNIV,MED CTR,DEPT MED,DIV CLIN PHARMACOL,DURHAM,NC
[4] DUKE UNIV,MED CTR,DEPT COMMUNITY & FAMILY MED,DIV BIOMETRY,DURHAM,NC 27710
[5] VET AFFAIRS MED CTR,CTR HLTH SERV RES PRIMARY CARE,DURHAM,NC
关键词
D O I
10.1001/archinte.155.3.277
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Our goal was to determine whether patient age affects a physician's reported likelihood of using anticoagulant therapy or the intensity of anticoagulant therapy for patients with nonvalvular atrial fibrillation. Methods: We surveyed a nationwide sample of 1189 randomly selected office-based practitioners in three strata: primary care (geriatrics, internal medicine, family practice, and general practice), cardiology, and neurology. A vignette-based questionnaire was used to measure attitudes and beliefs regarding anticoagulation risks and effectiveness, barriers to anticoagulation in clinical practice, and likelihood of using anticoagulation and target intensity of anticoagulation at three patient ages (55, 65, and 75 years) for four clinical scenarios (chronic nonvalvular atrial fibrillation with mild left atrial enlargement, intermittent or paroxysmal atrial fibrillation, recent-onset atrial fibrillation, and atrial fibrillation with recent [3 months] embolic stroke). Results: The overall response rate was 38%. The mean were ''very'' or ''somewhat'' likely to use anticoagulant therapy for a 65-year-old with left atrial enlargement (71%), intermittent or paryoxysmal atrial fibrillation (68%), recent-onset atrial fibrillation (86%), or embolic stroke (96%). Fewer physicians were likely to use anticoagulant therapy for a 75-year-old with left atrial enlargement (63%), intermittent or paroxysmal atrial fibrillation (56%), recent-onset atrial fibrillation (80%), or embolic stroke (93%). Among physicians equally likely to use anticoagulation for 65- and 75-year-old patients, intensity of anticoagulant therapy (target international normalized ratio or prothrombin time ratio) was lower (P<.04) for the 75-year-old. Conclusion: Anticoagulant therapy may be less often and less intensively used for elderly patients with nonvalvular atrial fibrillation.
引用
收藏
页码:277 / 281
页数:5
相关论文
共 27 条
  • [1] [Anonymous], 1994, LANCET, V343, P687
  • [2] CHANG HJ, 1990, ARCH INTERN MED, V150, P81
  • [3] CANADIAN ATRIAL-FIBRILLATION ANTICOAGULATION (CAFA) STUDY
    CONNOLLY, SJ
    LAUPACIS, A
    GENT, M
    ROBERTS, RS
    CAIRNS, JA
    JOYNER, C
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1991, 18 (02) : 349 - 355
  • [4] WARFARIN IN THE PREVENTION OF STROKE ASSOCIATED WITH NONRHEUMATIC ATRIAL-FIBRILLATION
    EZEKOWITZ, MD
    BRIDGERS, SL
    JAMES, KE
    CARLINER, NH
    COLLING, CL
    GORNICK, CC
    KRAUSESTEINRAUF, H
    KURTZKE, JF
    NAZARIAN, SM
    RADFORD, MJ
    RICKLES, FR
    SHABETAI, R
    DEYKIN, D
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1992, 327 (20) : 1406 - 1412
  • [5] RISK-FACTORS FOR COMPLICATIONS OF CHRONIC ANTICOAGULATION - A MULTICENTER STUDY
    FIHN, SD
    MCDONELL, M
    MARTIN, D
    HENIKOFF, J
    VERMES, D
    KENT, D
    WHITE, RH
    [J]. ANNALS OF INTERNAL MEDICINE, 1993, 118 (07) : 511 - 520
  • [6] RISK-FACTORS FOR STROKE AND OTHER EMBOLIC EVENTS IN PATIENTS WITH NONRHEUMATIC ATRIAL-FIBRILLATION
    FLEGEL, KM
    HANLEY, J
    [J]. STROKE, 1989, 20 (08) : 1000 - 1004
  • [7] FORFAR JC, 1979, BRIT HEART J, V42, P128
  • [8] AGING AND THE ANTICOAGULANT RESPONSE TO WARFARIN THERAPY
    GURWITZ, JH
    AVORN, J
    ROSSDEGNAN, D
    CHOODNOVSKIY, I
    ANSELL, J
    [J]. ANNALS OF INTERNAL MEDICINE, 1992, 116 (11) : 901 - 904
  • [9] ORAL ANTICOAGULANTS - MECHANISM OF ACTION, CLINICAL EFFECTIVENESS, AND OPTIMAL THERAPEUTIC RANGE
    HIRSH, J
    DALEN, JE
    DEYKIN, D
    POLLER, L
    [J]. CHEST, 1992, 102 (04) : S312 - S326
  • [10] OPTIMAL THERAPEUTIC RANGE FOR ORAL ANTICOAGULANTS
    HIRSH, J
    POLLER, L
    DEYKIN, D
    LEVINE, M
    DALEN, JE
    [J]. CHEST, 1989, 95 (02) : S5 - S11