APPLICABILITY OF CAPILLARY ZONE ELECTROPHORESIS TO STUDY METAL COMPLEXATION IN SOLUTION

被引：28

作者：

ERIM, FB ^{[1
]}

BOELENS, HFM ^{[1
]}

KRAAK, JC ^{[1
]}

机构：

[1] UNIV AMSTERDAM,ANALYT CHEM LAB,1018 WV AMSTERDAM,NETHERLANDS

来源：

ANALYTICA CHIMICA ACTA | 1994年 / 294卷 / 02期

关键词：

CAPILLARY ZONE ELECTROPHORESIS; METAL COMPLEXES; STABILITY CONSTANTS; NEUTRAL LIGANDS;

D O I：

10.1016/0003-2670(94)80190-8

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The suitability of capillary zone electrophoresis for the determination of stability constants of metal complexes was investigated. Three variants were tested viz., the frontal analysis, the Hummel-Dreyer method and the vacancy peak method, in the step-wise complexation between copper(II) and 1,10-phenanthroline as well as 2,2'-bipyridyl. The investigation reveals that CZE has attractive features for the quantitative study of complex formation with neutral ligands. However, the full exploitation requires more sensitive detection systems and application of an automated CZE system.

引用

页码：155 / 163

页数：9

共 9 条

[1] Z-SHAPED FLOW CELL FOR UV-DETECTION IN CAPILLARY ELECTROPHORESIS [J].

CHERVET, JP ;

VANSOEST, REJ ;

URSEM, M .

JOURNAL OF CHROMATOGRAPHY, 1991, 543 (02) :439-449

[2]

DRAPER NR, 1966, APPLIED REGRESSION A, P273

[3]

Hartley F. R., 1980, SOLUTION EQUILIBRIA

[4] ZONE ELECTROPHORESIS IN OPEN-TUBULAR GLASS-CAPILLARIES [J].

JORGENSON, JW ;

LUKACS, KD .

ANALYTICAL CHEMISTRY, 1981, 53 (08) :1298-1302

[5] STUDY OF PROTEIN DRUG-BINDING USING CAPILLARY ZONE ELECTROPHORESIS [J].

KRAAK, JC ;

BUSCH, S ;

POPPE, H .

JOURNAL OF CHROMATOGRAPHY, 1992, 608 (1-2) :257-264

[6]

Martel A.E., 1982, CRITICAL STABILITY C, V5

[7]

Press WH, 1986, NUMERICAL RECIPES AR, P521

[8] SEPARATION PROCEDURES USED TO REVEAL AND FOLLOW DRUG PROTEIN-BINDING [J].

SEBILLE, B ;

ZINI, R ;

MADJAR, CV ;

THUAUD, N ;

TILLEMENT, JP .

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1990, 531 :51-77

[9]

VEENING H, 1983, ADV CHROMATOGRAPHY, V22

← 1 →