CHOLESTASIS INDUCED BY HYPERTHYROIDISM AFTER LIVER-TRANSPLANTATION

被引：4

作者：

LERSCH, C

SEIGE, M

NATRATH, W

HEIDECKE, W

WITTEKIND, C

CLASSEN, M

SCHEPP, W

机构：

[1] TECH UNIV MUNICH,DEPT SURG,MUNICH,GERMANY

[2] TECH UNIV MUNICH,DEPT PATHOL,MUNICH,GERMANY

[3] UNIV ERLANGEN NURNBERG,DEPT PATHOL,W-8520 ERLANGEN,GERMANY

来源：

DIGESTION | 1995年 / 56卷 / 05期

关键词：

HYPERTHYROIDISM; CHOLESTASIS; LIVER TRANSPLANTATION;

D O I：

10.1159/000201271

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

We report the case of a 68-year-old woman who underwent liver transplantation because of hepatitis-C-induced cirrhosis. She developed iodine-induced hyperthyroidism postoperatively in temporal relation with cholestatic jaundice. Hepatic biopsies revealed moderate intrahepatic cholestasis and mild lobular inflammatory infiltration with some eosinophils. No histological evidence of acute graft rejection or reactivated hepatitis was found. Treatment with methimazole markedly reduced the serum parameters of cholestasis which, after subtotal thyroidectomy, returned to normal. Liver function recovered, as confirmed by repeated aminopyrine breath tests.

引用

页码：429 / 432

页数：4

共 19 条

[1]

Alter HJ, 1978, VIRAL HEPATITIS, P359

[2]

ARNOLD JC, 1992, TRANSPLANT P, V24, P2646

[3] RECURRENT HCV HEPATITIS AFTER LIVER-TRANSPLANTATION [J].

BELLI, LS ;

RONDINARA, GF ;

ROMANI, F ;

ALBERTI, A ;

DECARLIS, L ;

IDEO, G ;

BELLI, L .

LANCET, 1993, 341 (8841) :378-379

[4] ALKALINE-PHOSPHATASE ISOENZYME PATTERNS IN HYPER-THYROIDISM [J].

COOPER, DS ;

KAPLAN, MM ;

RIDGWAY, EC ;

MALOOF, F ;

DANIELS, GH .

ANNALS OF INTERNAL MEDICINE, 1979, 90 (02) :164-168

[5] ANTITHYROID DRUGS [J].

COOPER, DS .

NEW ENGLAND JOURNAL OF MEDICINE, 1984, 311 (21) :1353-1362

[6]

DONNER HP, 1967, ARCH INTERN MED, V120, P25

[7] LIVER IN THYROTOXICOSIS [J].

DOONER, HP ;

PARADA, J ;

ALIAGA, C ;

HOYL, C .

ARCHIVES OF INTERNAL MEDICINE, 1967, 120 (01) :25-+

[8] METHIMAZOLE-INDUCED JAUNDICE [J].

FISCHER, MG ;

NAYER, HR ;

MILLER, A .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1973, 223 (09) :1028-1029

[9] HYPERTHYROIDISM AND HEPATIC-DYSFUNCTION - A CASE SERIES ANALYSIS [J].

FONG, TL ;

MCHUTCHISON, JG ;

REYNOLDS, TB .

JOURNAL OF CLINICAL GASTROENTEROLOGY, 1992, 14 (03) :240-244

[10]

Habershon S.O., 1874, LANCET, V1, P510, DOI DOI 10.1016/S0140-6736(02)45227-0

← 1 2 →