MIDAZOLAM REDUCES VOMITING AFTER TONSILLECTOMY IN CHILDREN

被引：69

作者：

SPLINTER, WM ^{[1
]}

MACNEIL, HB ^{[1
]}

MENARD, EA ^{[1
]}

RHINE, EJ ^{[1
]}

ROBERTS, DJ ^{[1
]}

GOULD, MH ^{[1
]}

机构：

[1] UNIV OTTAWA,DEPT ANAESTHESIA,OTTAWA,ON K1H 8L1,CANADA

来源：

CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE | 1995年 / 42卷 / 03期

关键词：

ANESTHESIA; COMPLICATIONS; SURGERY; TONSILLECTOMY; ADENOIDECTOMY; VOMITING; POSTOPERATIVE; ANTIEMETICS; MIDAZOLAM;

D O I：

10.1007/BF03010676

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

The purpose of this study was to assess the effect of midazolam on vomiting after tonsillectomy in children. We compared 215 children aged 1.5-14 yr undergoing tonsillectomy or adenotonsillectomy under general anaesthesia with nitrous oxide and halothane. In a double-blind fashion the subjects were administered either placebo or midazolam 75 mu g.kg(-1) iv after induction of anaesthesia. After the operation, the number of emetic episodes and the length of stay in hospital were recorded. The groups were similar with respect to age, weight, sex, mode of induction, duration of anaesthesia, surgical procedure, opioid administration and length of stay in the PAR and the Day Care Surgical Unit. The 108 midazolam-treated children had a lower incidence (42% vs 57%) of vomiting than the placebo group, P < 0.02. The placebo group had a higher incidence (9% vs 2% of unscheduled admissions to hospital due to nausea and vomiting, P < 0.05. It is concluded that midazolam administered intravenously to children intraoperatively reduces vomiting after tonsillectomy.

引用

页码：201 / 203

页数：3

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