PULMONARY VASCULITIS IN BEHCETS-DISEASE

被引:55
作者
ERKAN, F [1 ]
CAVDAR, T [1 ]
机构
[1] ISTANBUL UNIV,ISTANBUL FAC MED,DEPT PNEUMOL,ISTANBUL,TURKEY
来源
AMERICAN REVIEW OF RESPIRATORY DISEASE | 1992年 / 146卷 / 01期
关键词
D O I
10.1164/ajrccm/146.1.232
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Clinical findings of 12 patients with Behcet's disease and lung involvement are presented. Male to female ratio was 11/1. mean age was 35.3 +/- 8.8 yr. All patients had at least four other organ manifestations of vasculitis, either in their history or during the period of lung involvement. The main complaint was hemoptysis of varying degree in 11 of the 12 patients. The chest X-ray films showed unilateral hilar enlargements in six patients, diaphragm elevation in four, horizontally or obliquely oriented linear opacities in three, diffuse, ill-defined infiltrates in upper and lower zones in three, wedge-shaped peripheral opacities in one, and bilateral pleural effusion in one patient. Computed tomography of the chest performed in nine patients revealed aneurysms, narrowings, and cutoffs of the main, lobar, segmental, or peripheral branches of the pulmonary artery and irregular configuration of other pulmonary vessels. Perfusion scans demonstrated defects of various sizes in all patients. Pulmonary angiography performed in only two patients showed amputation of branches of the pulmonary artery and aneurysmal dilatations. The patients were treated with a combination therapy consisting of corticosteroid, cyclophosphamide, colchicine. and antiaggregants, with very good results in the short term.
引用
收藏
页码:232 / 239
页数:8
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