INHIBITION BY ANTIHISTAMINES OF VASCULAR PERMEABILITY INCREASE INDUCED BY BRADYKININ

被引:41
作者
BECKER, EL
MOTA, I
WONG, D
机构
[1] Department of Immunochemistry, Walter Reed Army Institute of Research, Washington, 20012, DC
关键词
D O I
10.1111/j.1476-5381.1968.tb07054.x
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Mepyramine and triprolidine hydrochloride have a marked inhibitory effect on the local increase of vascular permeability induced by bradykinin. The anti-bradykinin effect of both antihistamines was species dependent, being evident in rabbits, rats and mice but not in guinea-pigs. © 1968 British Pharmacological Society.
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页码:330 / &
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