AN INSTRUMENT FOR QUANTIFYING MEIBOMIAN LIPID ON THE LID MARGIN - THE MEIBOMETER

被引:74
作者
CHEW, CKS
JANSWEIJER, C
TIFFANY, JM
DIKSTEIN, S
BRON, AJ
机构
[1] UNIV OXFORD,NUFFIELD LAB OPHTHALMOL,WALTON ST,OXFORD OX2 6AW,ENGLAND
[2] HEBREW UNIV JERUSALEM,SCH PHARM,CELL PHARMACOL UNIT,JERUSALEM,ISRAEL
基金
英国惠康基金;
关键词
D O I
10.3109/02713689308999470
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
An instrument, the Meibometer, is described for estimating the casual level of meibomian lipid on the human eyelid margins, adapted from a commercially-available instrument used for measurement of skin surface lipid. A loop of plastic tape is pressed onto the everted lower lid margin to lift off a blot of lipid. The resultant change in light transmission of the tape is read by a photometer. Readings are not affected by side (R or L), time of day or lid surface temperature. After cleaning lipid from the lid margins with hexane, the rate of recovery per 10 blinks, as a percentage of the pre-cleaned level, was measured as 33.7 +/- 5.8 (mean +/- SE). This rate of delivery appears to provide enough lipid for complete resurfacing of the preocular tear film with every blink. Over short periods no detectable lipid was delivered in the absence of blinking.
引用
收藏
页码:247 / 254
页数:8
相关论文
共 25 条
[1]  
BRON A J, 1991, Eye (London), V5, P395
[2]   VARIABILITY IN CHEMICAL COMPOSITION OF HUMAN SKIN SURFACE LIPIDS [J].
DOWNING, DT ;
STRAUSS, JS ;
POCHI, PE .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1969, 53 (05) :322-&
[3]  
FRANCK C, 1991, ACTA OPHTHALMOL, V69, P737
[4]  
Guillon JP, 1986, PREOCULAR TEAR FILM, P914
[5]  
Hamano H, 1979, J JAPANESE CONTACT L, V21, P229
[6]  
HOLLY F J, 1973, International Ophthalmology Clinics, V13, P73
[7]  
HOLLY FJ, 1985, T OPHTHAL SOC UK, V104, P374
[8]   AGE-RELATED MORPHOLOGICAL-CHANGES IN LID MARGIN AND MEIBOMIAN GLAND ANATOMY [J].
HYKIN, PG ;
BRON, AJ .
CORNEA, 1992, 11 (04) :334-342
[9]  
JOSEPHSON JE, 1983, AM J OPTOM PHYS OPT, V60, P883
[10]  
KILP M, 1982, KLIN MBL AUGENHEILK, V180, P49