ANTHRACYCLINES AND RELATED SUBSTANCES .2. EFFICIENT AND REGIOSPECIFIC SYNTHESIS OF DL-7,9-DIDEOXYDAUNOMYCINONE

被引：45

作者：

KIM, KS

VANOTTI, E

SUARATO, A

JOHNSON, F

机构：

[1] SUNY STONY BROOK,DEPT PHARMACOL SCI,STONY BROOK,NY 11794

[2] SUNY STONY BROOK,DEPT CHEM,STONY BROOK,NY 11794

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1979年 / 101卷 / 09期

关键词：

D O I：

10.1021/ja00503a041

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Of the group of compounds that comprise the anthracyclines,2two substances, namely daunomycin3(1) and adri-amycin4(2), have achieved preeminence as antitumor agents, despite the fact that they frequently induce an irreversible cardiomyopathy. This has initiated a search for partially or totally synthetic derivatives that might lack this side effect.5. © 1979, American Chemical Society. All rights reserved.

引用

页码：2483 / 2484

页数：2

共 21 条

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