MASTOPARAN INCREASES MEMBRANE-BOUND PHOSPHATIDYLINOSITOL KINASE AND PHOSPHATIDYLINOSITOL 4-MONOPHOSPHATE KINASE-ACTIVITIES IN MADIN-DARBY CANINE KIDNEY-CELLS

被引：10

作者：

ENG, SP

LO, CS

机构：

[1] Department of Physiology Uniformed Services University of the Health Sciences, Bethesda, MD 20814-4799

来源：

LIFE SCIENCES | 1990年 / 46卷 / 04期

关键词：

D O I：

10.1016/0024-3205(90)90033-N

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Synthetic wasp venom Mastroparan induced an increase of[3H] inositol phosphates levels and a corresponding decrease of [3H] inositol phospholipids levels in Madin-Darby canine kidney (MDCK) cells. The effect was dose (5-100 μg/m1) and time (1 to 15 min) dependent. Mastoparan also enhanced the endogenous activity of phosphatidylinositol kinase and phosphatidylinositol 4-monophosphate kinase. The effect was dose (25-75 μg/m1) and time dependent (1 to 15 min). © 1990.

引用

页码：273 / 279

页数：7

共 18 条

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