HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ASSAY OF THIOMERSAL (THIMEROSAL) AS THE ETHYLMERCURY DITHIOCARBAMATE COMPLEX

被引：12

作者：

PARKIN, JE

机构：

[1] School of Pharmacy, Curtin University of Technology, Bentley, WA 6102, Kent Street

来源：

JOURNAL OF CHROMATOGRAPHY | 1991年 / 542卷 / 01期

关键词：

D O I：

10.1016/S0021-9673(01)88754-9

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A high-performance liquid chromatographic (HPLC) assay has been developed for the ethylmercury ligand of thiomersal (thimerosal) as either the morpholine or piperidinedithiocarbamate complexes. The assay has been compared with a previously reported HPLC assay of thiomersal for organomercurical degraded both thermally and photochemically, and significant differences are noted.

引用

页码：137 / 143

页数：7

共 26 条

[1]

DAVIES DJG, 1983, 3RD EXP C INT TECHN, V4, P238

[2] QUANTITATIVE HIGH-PRESSURE LIQUID-CHROMATOGRAPHIC DETERMINATION OF THIMEROSAL IN PHARMACEUTICAL FORMULATIONS [J].

FU, CC ;

SIBLEY, MJ .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1977, 66 (05) :738-739

[3]

HOLAK W, 1983, J ASSOC OFF ANA CHEM, V66, P1203

[4]

HORWORKA K, 1973, PHARMAZIE, V28, P136

[5] REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF DIETHYLDITHIOCARBAMATE COMPLEXES USING RADIAL COMPRESSION COLUMNS [J].

HUTCHINS, SR ;

HADDAD, PR ;

DILLI, S .

JOURNAL OF CHROMATOGRAPHY, 1982, 252 (DEC) :185-192

[6]

IBRAHIM SN, 1981, J PHARM PHARMACOL, V33, pP7

[7]

KIMPTON R G, 1987, Australian Journal of Hospital Pharmacy, V17, P191

[8]

Lam S W, 1981, J Parenter Sci Technol, V35, P262

[9]

LUDTKE E, 1977, PHARMAZIE, V32, P625

[10]

LUDTKE E, 1977, PHARMAZIE, V32, P99

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