GM-2 GANGLIOSIDOSIS (SANDHOFFS DISEASE) - 2-YEAR FOLLOW-UP BY MRI

被引：28

作者：

KOELFEN, W ^{[1
]}

FREUND, M ^{[1
]}

JASCHKE, W ^{[1
]}

KOENIG, S ^{[1
]}

SCHULTZE, C ^{[1
]}

机构：

[1] RADIOL KLIN, MANNHEIM, GERMANY

来源：

NEURORADIOLOGY | 1994年 / 36卷 / 02期

关键词：

GM-2; GANGLIOSIDOSES; SANDHOFFS DISEASE; MRI;

D O I：

10.1007/BF00588086

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Two children with GM-2 gangliosidosis type 0 (Sandhoff's disease) followed up by MRI at 1.5 Tesla for 1.8 years are reported. One was presymptomatic at the first MRI examination. As her neurological status deteriorated, MRI showed low signal in bilaterally, on T2-weighted images the white matter with involvement of the optic radiations. In the second, MRI correlated well with the clinical progression of the disease, showing in the different stages involvement of thalamus and basal ganglia. There was no contrast enhancement and the grey matter remained normal.

引用

页码：152 / 154

页数：3

共 20 条

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