ANTITHROMBIN-3 - PROTECTION AGAINST DEATH AFTER INJECTION OF THROMBOPLASTIN

被引：31

作者：

MANN, LT

JENSENIUS, JC

SIMONSEN, M

ABILDGAARD, U

机构：

[1] Institute for Experimental Immunology, 2100 Copenhagen Ø

[2] Haematological Research Laboratory, Ullevaal Hospital

来源：

SCIENCE | 1969年 / 166卷 / 3904期

关键词：

D O I：

10.1126/science.166.3904.517

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Intravenous injection of autologous lipoprotein (thromboplastin) or thrombin produced a lethal, hemorrhagic syndrome in chicken embryos. The embryos could be protected from this fatal result by injection of antithrombin III, an alpha2-globulin (molecular weight 60,000 to 80,000) purified from human, bovine, and guinea pig blood. Heparin also protected the embryos, but other inhibitors were less protective.

引用

页码：517 / +

页数：1

共 9 条

[1] HIGHLY PURIFIED ANTITHROMBIN 3 WITH HEPARIN COFACTOR ACTIVITY PREPARED BY DISC ELECTROPHORESIS
ABILDGAARD, U
[J]. SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION, 1968, 21 (01) : 89 - +
[2] PURIFICATION OF 2 PROGRESSIVE ANTITHROMBINS OF HUMAN PLASMA
ABILDGAARD, U
[J]. SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION, 1967, 19 (02) : 190 - +
[3] INHERITED ANTITHROMBIN DEFICIENCY CAUSING THROMBOPHILIA
EGEBERG, O
[J]. THROMBOSIS ET DIATHESIS HAEMORRHAGICA, 1965, 13 (3-4): : 516 - &
[4] LANCHANTIN GF, 1966, P SOC EXP BIOL MED, V121, P444
[5] SOME EXPERIMENTAL FACTORS IN GRADIENT CHROMATOGRAPHY OF SERUM PROTEINS
PETERSON, EA
CHIAZZE, EA
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1962, 99 (01) : 136 - &
[6] THE ACTIVE PRINCIPLE OF PLACENTAL TOXIN - THROMBOPLASTIN - ITS INACTIVATOR IN BLOOD - ANTITHROMBOPLASTIN
SCHNEIDER, CL
[J]. AMERICAN JOURNAL OF PHYSIOLOGY, 1947, 149 (01): : 123 - 129
[7] STEINBUCH M, 1968, REV FR ETUD CLIN BIO, V13, P179
[8] THOMAS L, 1947, B JOHNS HOPKINS HOSP, V81, P26
[9] ZALESKI M, 1968, FOLIA BIOL-PRAGUE, V14, P176

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