HPLC QUANTIFICATION OF AZINTAMIDE AND PAPAVERINE HYDROCHLORIDE SIMULTANEOUSLY IN PHARMACEUTICAL PREPARATIONS

被引：2

作者：

ABOUNASSIF, MA

ABDELMOETY, EM

GADKARIEM, EA

机构：

[1] Pharmaceutical Chemistry Department, College of Pharmacy, King Saud University, Riyadh, 11A51

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1990年 / 13卷 / 13期

关键词：

D O I：

10.1080/01483919008049063

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A simple HPLC-procedure for quantification of azintamide and papaverine.HC1 simultaneouly in dosage formulations has been investigated. The complete resolution and quantitative determination of both drug substances has been undertaken on a Hibar 100RP-18 Lichrospher (5 pm) column by using a solvent mixture composed of acetonirile - water (56:44, v/v) isocratically at a rate of 1 ml.min-1 with UV-detection at 240 nm. Recovery percentages of 100.39 ± 0.70 (n = 12) and 99.97 + 1.11 (n = 12) were obtained for added azintamide and papaverine.HCl, in order. © 1990, Taylor & Francis Group, LLC. All rights reserved.

引用

页码：2689 / 2698

页数：10

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