LIFE-SPAN OF LYMPHOCYTES

被引：79

作者：

TOUGH, DF ^{[1
]}

SPRENT, J ^{[1
]}

机构：

[1] Scripps Res Inst, DEPT IMMUNOL, IMM4, LA JOLLA, CA 92037 USA

来源：

IMMUNOLOGIC RESEARCH | 1995年 / 14卷 / 01期

关键词：

LYMPHOCYTE LIFE-SPAN; IMMUNE MEMORY; BROMODEOXYURIDINE; T-CELL TURNOVER; B-CELL TURNOVER;

D O I：

10.1007/BF02918494

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

T and B lymphocytes comprise heterogeneous populations of cells at various stages of differentiation and activation. T- and B-cell subsets have different roles in the maintenance of immune homeostasis, and their functional differences are reflected by their respective lifespans. This review briefly summarizes the available data on lymphocyte lifespan, including the kinetics of T- and B-cell development in the primary lymphoid organs and the proliferative behavior of naive, effector and memory lymphocytes in the peripheral lymphoid compartment.

引用

页码：1 / 12

页数：12

共 73 条

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