ACUTE MONOCYTIC LEUKEMIA WITH (8 22)(P11 Q13) TRANSLOCATION - INVOLVEMENT OF 8P11 AS IN CLASSICAL T(8 16)(P11 P13)

被引：34

作者：

LAI, JL

ZANDECKI, M

FENAUX, P

PREUDHOMME, C

FACON, T

DEMINATTI, M

机构：

[1] HOP CALMETTE LILLE,HEMATOL LAB,LILLE,FRANCE

[2] HOP HURIEZ LILLE,SERV MALAD DU SANG,LILLE,FRANCE

来源：

CANCER GENETICS AND CYTOGENETICS | 1992年 / 60卷 / 02期

关键词：

D O I：

10.1016/0165-4608(92)90013-X

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A new case of acute monocytic leukemia observed in a 73-year-old male (ANLLM5) with an unusual t(8;22)(p11;q13) is reported. The blasts did not demonstrate erythrophagocytosis, but the presence of both naphtol-ASD-chloro-acetate esterase and butyrate esterase activities was similar to that seen in cases with t(8;16)(p11;p13).Involvement of the 8p11 region in ANLLM4 and M5 is discussed, being the third most frequent rearrangement in acute leukemia with monocytic components seen at our Center.

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页码：180 / 182

页数：3

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